WebJul 1, 2002 · The histone deacetylase inhibitor sodium butyrate interacts synergistically with phorbol myristate acetate (PMA) to induce mitochondrial damage and apoptosis in human myeloid leukemia cells through a tumor necrosis factor-alpha-mediated process WebThe precursor protected in the 20-hydroxyl group of phorbol was acylated by [1-11 C]propyl ketene to the 13-hydroxyl group producing phorbol 13-[11 C]butyrate ([11 C]P13Bu). Total synthesis time was about 60 minutes and the specific activity was greater than 67 GBq/μmol (1800 mCi/μmol).
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WebStructure, properties, spectra, suppliers and links for: 4β-Phorbol 12,13-dibutyrate, Phorbol 12,13-dibutyrate, 37558-16-0. Jump to main content Jump to site nav Home Web[(1S,2S,6R,10S,11R,13S,14R,15R)-1,6,14-trihydroxy-8-(hydroxymethyl)-4,12,12,15-tetramethyl-5-oxo-13-tetracyclo[8.5.0.02,6.011,13]pentadeca-3,8-dienyl] butanoate
WebButyrate acts as a differentiating agent [25] and activates PKC [26]. Interestingly, phorbol esters, similar to butyrate, exhibit differentiating potential involving activation of PKC [27]. …
WebPhorbol 12,13-dibutyrate C28H40O8 CID 37783 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological ... Webphorbol-diester hydrolase Alternative Name(s) diacylphorbate 12-hydrolase: Reaction catalysed; H2O + phorbol 12,13-dibutanoate => butanoate + H(+) + phorbol 13-butanoate: …
WebPhorbol 12,13-dibutyrate (PDB), a potent activator of protein kinase C … Polymyxin B, a selective inhibitor of protein kinase C, diminishes the release of noradrenaline and the enhancement of release caused by phorbol 12,13-butyrate Naunyn Schmiedebergs Arch Pharmacol. 1986 Oct;334(2):218-21. doi: 10.1007/BF00505825. ...
WebAug 1, 2024 · Tiglilane diterpene group compounds such as phorbol-12-decanoate, phorbol-12,13,20-triacetate, 12-O-tetradecanoylphorbol-13-acetate, and others. Compounds of this type had been reported antivirals activities such as anti-HIV-1 and anti-HIV-2 ( Nothias-Scaglia et al., 2015; Olivon et al., 2015 ). earth balloonWebphorbol 13-butanoate (1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-4a,7b,9-trihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1,1a,1b,4,4a,5,7a,7b,8,9-decahydro-9aH … ct dmv renew learners permitWebPhorbol 12,13-dibutyrate (PDBu) is a phorbol ester which is one of the constituents of croton oil. As an activator of protein kinase C, it is a weak tumor promoter compared to 12-O … ct dmv selling car to familyWebChemical Entities of Biological Interest (ChEBI) is a freely available dictionary of molecular entities focused on 'small' chemical compounds. phorbol 13-butanoate (CHEBI:17727) … ct dmv schedulingWebEC: 3.1.1.51 : Accepted name: phorbol-diester hydrolase: Reaction: phorbol 12,13-dibutanoate + H 2 O = phorbol 13-butanoate + butanoate: For diagram of reaction, click here Other name(s): diacylphorbate 12-hydrolase; diacylphorbate 12-hydrolase; phorbol-12,13-diester 12-ester hydrolase; PDEH ct dmv sale of vehicleWebJul 1, 2002 · Abstract. Interactions between the histone deacetylase inhibitor sodium butyrate (SB) and phorbol 12-myristate 13-acetate (PMA) were examined in human … ct dmv selling a car without a titleWebPhorbol-13-butyrate C24H34O7 CID 126455852 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, … ct dmv selling car after death