Mitoferrin-2

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August undefined, 2024

Webmitoferrin-2 Gene provides a unified query environment for genes defined by sequence and/or in NCBI's Map Viewer. LOC104273912 mitoferrin-2 [ (bar-tailed trogon)] WebObjective To construct the prokaryotic expression plasmid of human mitoferrin 2 (SLC25A28), and to express and purify the protein for preparing its rabbit polyclonal antibody. Methods The prokaryotic expression plasmid pET28a(+)-SLC25A28-His was constructed and transferred into E. coli BL21 (DE3), and induced with Isopropyl-β-D …

Iron Regulatory Protein-1 Protects against Mitoferrin-1-deficient ...

Web26 sep. 2014 · Mitoferrin-2 siRNA was designed and purchased from GenePharma (Shanghai, China). Annexin V-FITC-PI apoptosis detection kit (Baosea Biotechnology … WebMitoferrin 2, also known as MRS3/4 (mitochondrial RNA-splicing protein 3/4 homolog), mitochondrial iron transporter 2, NPD016, MRS4L or SLC25A28 (solute carrier family 25 member 28), is a 364 amino acid multi-pass membrane protein of the mitochondrial inner membrane that mediates iron uptake. Mitoferrin 2 is thought to play a role in heme … richard reddick tx

SLC25A28 Gene - GeneCards MFRN2 Protein MFRN2 Antibody

Web康朗生物为您提供液泡蛋白分选蛋白4b抗体的参数及2024年最新报价，厂家专业的液泡蛋白分选蛋白4b抗体售后服务团队，是您 ... WebTwo mitoferrin proteins, mitoferrin-1 (MFRN1; encoded by the solute carrier family 25-member 37 gene [SLC25A37]) and mitoferrin-2 (MFRN2; encoded by SLC25A28), are … WebHere, we investigated the role of the mitochondrial iron transporters mitoferrin-1 (MFRN1) and mitoferrin-2 (MFRN2) in GBM progression. Analysis of The Cancer Genome Atlas database revealed upregulation of MFRN1 mRNA and downregulation of MFRN2 mRNA in GBM tumor tissue compared with non-GBM tissue, yet only the tumor expression level of … richard redfern richland ms

Mitoferrin, Cellular and Mitochondrial Iron Homeostasis

Cryo-EM structures of mitochondrial ABC transporter ABCB10 in …

Web9 jun. 2024 · to as Mitoferrin 2 (Mfrn2)) hav e been. implicated in iron import into . mitochondria (4-8). Paralogous . genes are found in all eukaryotes. Plants, C aenorhabditis elegans an d . Web12 aug. 2015 · Iron transported into mitochondria by mitoferrins is mainly utilized for the biosynthesis of iron-sulfur clusters, heme, and other cofactors. Recent studies revealed that mitochondrial dysfunction leads to impaired adipogenesis and … richard reddie abolitionWeb22 sep. 2009 · PN Paradkar, et al., Regulation of mitochondrial iron import through differential turnover of mitoferrin 1 and mitoferrin 2. Mol Cell Biol 29, 1007–1016 … richard redden hair

"Web2 nov. 2024 · Iron is also required for the production of mitochondrial complexes that contain these iron-sulfur clusters and heme. As the principal iron importers in the mitochondria of … " - Mitoferrin-2

Mitoferrin-2

Web29 mrt. 2024 · Mitoferrin-2-dependent mitochondrial iron uptake sensitizes human head and neck squamous carcinoma cells to photodynamic therapy; Observational study of gene … Web1 mei 2024 · Mitoferrin 2 (Mfrn2) is an iron transporter in the inner mitochondrial membrane. This study aimed to assess whether Mfrn2 and mitochondrial iron overload were involved in atherosclerosis progression and to explore the potential mechanism.

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WebApplication Instructions Properties Bioinformation Images (2) Click the Picture to Zoom In ARG41960 anti-SLC25A28 / Mitoferrin 2 antibody IHC-P image Immunohistochemistry: … Webmitochondrial iron uptake through mitoferrin-2 (Mfrn2) enhanced PDT-induced cell killing. Three human head and neck squamous carcinoma cell lines (UMSCC1, UMSCC14A, …

WebMitoferrin-1 (UniProt Q920G8; also known as mitochondrial iron transporter 1, mitochondrial solute carrier protein, solute carrier family 25 member 37) is encoded by the Slc25a37 (also known as Mfrn, Mfrn1, Mscp) gene (Gene ID 67712) in murine species. Mitoferrin-1 and mitoferrin-2 (Slc25a28, Mfrn2) mediate iron import into mitochondria. Web1 mei 2024 · Mitoferrin 2 (Mfrn2) is an iron transporter in the inner mitochondrial membrane. This study aimed to assess whether Mfrn2 and mitochondrial iron overload …

WebMitoferrin-1 (Mfrn1) is a 38 kDa protein [5] that is encoded by the SLC25A37 gene in humans. [6] [7] It is a member of the Mitochondrial carrier (MC) Superfamily, however, its … Web20 dec. 2024 · Here, we show that human sideroflexin 2 (SFXN2), a member of the SFXN protein family, is involved in mitochondrial iron metabolism. SFXN2 is an evolutionarily …

Web2, encoded by the transmembrane serine protease 6 (TMPRSS6) gene and the erythroid-released hormone, ery-throferrone (ERFE). In iron deﬁciency, matriptase 2 inhibits hepcidin by cleaving the BMP co-receptor HJV on the hepa-tocyte membrane (Silvestri et al, 2008). Cleavage of other substrates, as recently proposed (Wahedi et al, 2024), seems

Web11 jan. 2012 · Mitoferrin 2 is ubiquitously expressed, whose functions are less known. Zebrafish with mitoferrin 1 mutation show profound hypochromic anaemia and erythroid … redman schwartz.comWeb2 nov. 2024 · Created with BioRender (Science Suite Inc., Toronto, ON, Canada). Two mitoferrins, mitoferrin-1 (encoded by the solute carrier family 25-member 37 gene, … redman schwartz aplingtonWeb17 mei 2024 · Furthermore, mitoferrin 2 and mitochondrial ferritin were also downregulated in the hearts from HF mice. Similar data regarding these key iron regulatory molecules were found in the H9c2 cells challenged with neurohormonal stimuli. redman scholarshipWebWang, D., Ye, P., Kong, C., Chao, Y., Yu, W., Jiang, X., … Chen, S.-L. (2024). Mitoferrin 2 deficiency prevents mitochondrial iron overload-induced endothelial ... richard redgraveWeb24 sep. 2024 · The production of excess mitochondrial ROS requires more iron to pass through the mitochondrial membrane. In U87MG and T98G cells treated with arsenic trioxide, expression levels of mitoferrin-2 increased four- to fivefold, while ROS production and apoptosis decreased in the cells with low expression of mitoferrin-2. Silencing … redmans chickenWebBackground: Here, we investigated whether iron mobilization enhanced photodynamic therapy (PDT)-induced cell killing.Results: Lysosomal iron release and mitochondrial iron uptake through mitoferrin-2 (Mfrn2) … redmans campsite wappapelloWeb21 mrt. 2024 · Mitoferrin 2 3 Solute Carrier Family 25, Member 37 2 Predicted Protein Of HQ2217 3 PRO1278 3 PRO1584 3 PRO2217 3 MSC 3 External Ids for SLC25A37 Gene … richard redlin actor