WebSummary: Some of the challenges in early stages of a pharmaceutical are a limited supply of protein to use in formulation screening studies, and a need to obtain stability data quickly to initiate tox studies. In this poster, scientists at Catalent Biologics outline a method utilizing a high-throughput, micro-well plate platform to economically screen a mAb in 96 … Weblenges. Automated high-throughput dynamic light scat-tering (HT–DLS) utilizing Wyatt Technology’s DynaPro Plate Reader II helps to streamline the pre-formulation process, and can be used as a standalone instrument or as part of a larger automated formulation workflow. Us-ing very low solution volume, HT–DLS enables rapid, un-

High throughput applications - AgfaLabs

WebKey Talent: A scientific investigator in high throughput experimentation with recognition both internally and externally as an expert in automated … Webthese methods are amenable to high throughput. DSF is a biophysical technique that is suitable for high-throughput screening with a minimal protein requirement. DSF … northolt surgery

(PDF) High-throughput screening techniques for preformulation: Salt …

WebSep 1, 2008 · Important factors for high-throughput protein formulation are: (i) minimizing the amount of protein needed, (ii) selecting the correct assay (s) and consumables, (iii) preparing formulations using an excipient library, (iv) integrating multiple automated techniques, (v) continuous data evaluation and (vi) flexibility in designing new experiments. WebContext: Freeze-drying in presence of excipients is a common practice to stabilize biomacromolecular formulations. The composition of this formulation is known to affect the quality of the final product. Objective: The aim of this study was to evaluate freeze-drying in well-plates as a high throughput platform for formulation screening of freeze-dried … WebHigh-throughput Studies can be considered from two perspectives: there are platforms that measure many datapoints per sample; there are also platforms that measure the … how to score in solitaire