Cisplatin atherosclerosis

WebFeb 1, 2024 · Cis-diamminedichloroplatinum (cisplatin) is an effective agent for treating solid tumors. However, its clinical use is limited by its serious toxic side effects; … WebSep 1, 2024 · Cohort 1: Early effects of cisplatin-based chemotherapy Vascular function Participant characteristics are presented in Table 1. %FMD decreased 24 h after the first dose of cisplatin in the 10 patients managed with 3 to 4 cycles of BEP (16.7 ± 1.6 at baseline vs. 10.9 ± 0.9 at 24 h after cisplatin; p = 0.003) ( Figure 2 ).

National Center for Biotechnology Information

WebOct 11, 2024 · Weakening of the heart muscle (cardiomyopathy) Heart rhythm problems (arrhythmia) Heart attack Stroke High blood pressure Blood clots Whether you're at risk … WebFeb 16, 2024 · severe or ongoing nausea and vomiting; vision problems, pain behind your eyes; hearing problems, ringing in your ears; pain, redness, swelling, or skin changes … china foam matt tiles https://pcdotgaming.com

Comprehensive review on how platinum- and taxane-based

WebAug 14, 2024 · Lipopolysaccharide (LPS) is an endotoxin that induces systemic inflammatory responses. Melittin, a main constituent of bee venom, exerts several biological activities such as antioxidant, anti-inflammatory, and antiapoptotic actions. However, whether melittin protects against endotoxin-induced AKI remains undetermined. WebDec 30, 2024 · Cisplatin causes direct and acute endothelial toxicity with a propensity to arterial thrombosis, irrespective of the presence of underlying atherosclerosis. … WebIn addition, BANCR induced the proliferation of vascular smooth muscle cells by downregulating miR-34c methylation in atherosclerosis. 34 Here, we could not exclude the possibility that BANCR may attenuate the killing capacity of cisplatin on GC cells by regulating miRNAs. Further investigation is needed in our future study. graham cooke prophetic soaking youtube

High dose ionizing radiation accelerates atherosclerotic plaque ...

Category:Hederagenin potentiated cisplatin- and paclitaxel-mediated

Tags:Cisplatin atherosclerosis

Cisplatin atherosclerosis

Early detection of acute cisplatin nephrotoxicity: interest of …

WebJul 29, 2024 · The cancer-therapeutic drug, cisplatin, induces the release of GDF15 and activates GFRAL AP/NTS neurons, as well as causing significant reductions in food intake and body weight in mice. These … WebNational Center for Biotechnology Information

Cisplatin atherosclerosis

Did you know?

WebModern hypotheses introduce atherosclerosis as an inflammatory/lipid-based disease and NLRP3 inflammasome has been considered as a link between lipid metabolism and inflammation because crystalline cholesterol and oxidized low-density lipoprotein (oxLDL) (two abundant components in atherosclerotic plaques) activate NLRP3 inflammasome. WebAtherosclerosis is characterized by vascular obstruction from the deposits of plaque, resulting in reduced blood flow. Plaque rupture and the consequent thrombosis may lead to sudden blockage of the arteries and cause heart attack.

WebQuick Search anywhere. Enter Search Terms Search. Quick Search in Journals WebOct 31, 2024 · It has been found that cisplatin may induce DNA damage and cancer cell death also by induction of oxidative stress, particularly the overproduction of mitochondrial reactive oxygen species (ROS) and by decreasing the pool of intracellular antioxidants, e.g. reduced glutathione (GSH).

WebNational Center for Biotechnology Information WebNational Center for Biotechnology Information

WebDec 1, 2024 · Europe PMC is an archive of life sciences journal literature.

WebOct 10, 2024 · Late adverse vascular effects of platinum drugs have been attributed to platinum-related disruptions of vascular endothelial cells resulting in a … graham cook se twentyWebCisplatin is also used alone or in combination with other medications to treat bladder cancer that can not be treated with surgery or radiation therapy alone. Cisplatin is in a class of … grahamcooley outlook.comWebJan 11, 2024 · High risk for progression includes those with a large plaque burden, a thin-cap fibroatheroma, low-attenuation, and positive vessel remodeling. Among patients with … graham cooke prophetic soakingWebMar 27, 2024 · Cisplatin (CisPt) is an alkylating drug that has been successfully used for decades to treat solid organ tumours such as lung, testis or ovarian cancers, resulting in an increased life expectancy for patients. graham cookson oheWebStatins were associated with slower progression of overall coronary atherosclerosis volume, with increased plaque calcification and reduction of high-risk plaque … graham cooke practicing the presence of godWebDec 30, 2024 · However, cardiovascular toxicity is a major concern. In addition to acute endothelial toxicity and associated risk of arterial thrombosis, accelerated atherosclerosis may be the result of chemotherapy-associated latent cardio-metabolic dysfunction. A 45-year-old man began treatment with cisplatin-based chemotherapy for testicular cancer. china foam play matWebDec 16, 2024 · Introduction: Cisplatin-based chemotherapeutic regimen (CBCR) is known for increasing risk of venous thromboembolic (TE) disease. We report a unique case of STEMI associated with CBCR which we believe was caused by coronary artery … china foam pillow