C-terminal binding protein 2
WebJan 8, 2024 · CtBP2 interacts with TGIF to promote the progression of esophageal squamous cell cancer through the Wnt/betacatenin pathway. The transcriptional … WebCarboxy-terminal (C-terminal) sequence analysis is used for direct confirmation of the C-terminal sequence of native and expressed proteins, for detection and characterization …
C-terminal binding protein 2
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Web2 days ago · A farnesyl or geranylgeranyl isoprenoid group is added to the cysteine in the C-terminal CAAX motif by farnesyltransferase (FTase ... mutation of K346 to alanine or glutamine decreases the binding of RAC1B to SmgGDS-558 (Fig. 2 C, lanes 3 and 5 ... Structure of the Rho family GTP-binding protein Cdc42 in complex with the … WebC-terminal binding protein‑2 (CtBP2) is a transcriptional co-repressor that is associated with tumorigenesis and tumor progression. It has been reported to predict a poor prognosis in several human cancers, including esophageal squamous cell.
WebCalponin 1 is a basic smooth muscle protein that in humans is encoded by the CNN1 gene.. The CNN1 gene is located at 19p13.2-p13.1 in the human chromosomal genome and contains 7 exons, encoding the protein calponin 1, an actin filament-associated regulatory protein. Human calponin 1 is a 33.2-KDa protein consists of 297 amino acids with an … WebOct 29, 2009 · Sequence analysis predicted that the 1,325-amino acid protein, like other ABC transporters, contains nucleotide-binding folds and 12 transmembrane-spanning helices in 2 hydrophobic domains. Northern blot analysis revealed ubiquitous expression of an approximately 6.0-kb transcript that is highest in prostate and lowest in liver and …
WebIsoform-2 contains 305 amino acids and has an N-terminal acyl-CoA-binding domain (ACBD), followed by a FFAT-like motif, a coiled-coil domain, and a C-terminal transmembrane domain and tail. Myc-tagged ACBD4 isoform-2 localized to peroxisomes in transfected COS-7 cells. Topology analysis revealed that isoform-2 was a C-terminal tail … WebJun 1, 2001 · Corepressor targeting diverse transcription regulators such as GLIS2 or BCL6. Has dehydrogenase activity. Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex. Functions in brown adipose tissue …
WebOct 25, 2024 · BACKGROUND Recent studies have illustrated that the transcription co-repressor, C-terminal binding protein 1 (CtBP1), links the metabolic alterations to transcription controls in proliferation, EMT, genome stability, metabolism, and lifespan, but whether CtBP1 affects the cellular redox homeostasis is unexplored. This study was …
WebNov 9, 2004 · PTHR46029:SF7 C-TERMINAL-BINDING PROTEIN 1 hit; PROSITE. View protein in PROSITE; PS00671 D_2_HYDROXYACID_DH_3 1 hit; Pfam. View protein in Pfam; PF00389 2-Hacid_dh 1 hit; PF02826 2-Hacid_dh_C 1 hit; SUPFAM. SSF52283 Formate/glycerate dehydrogenase catalytic domain-like 1 hit; cinci outletsWebAug 21, 2024 · Earlier, we reported that some bMERB family members have two Rab-binding sites, a high-affinity C-terminal binding site, and a lower or similar affinity N-terminal binding site 4,5. cinci.rr.com email server settingsWebFeb 4, 2024 · C-terminal binding protein (CtBP) 1 and 2 are transcriptional coregulators that repress diverse cellular processes. Unexpectedly, we find that the CtBPs can transactivate a common set of proinflammatory genes both in lipopolysaccharide-activated microglia, astrocytes and macrophages, and in a mouse model of the mild form of TBI. ... di2 wireless moduleWebMar 20, 2024 · BMP7 rapidly activates c-Jun N-terminal kinases (JNKs), known regulators of microtubule dynamics, and we show that JNKs associate with the carboxy terminus of the BMP receptor, BMPRII. Activation and binding of JNKs to BMPRII is required for BMP7-induced microtubule stabilization and for BMP7-mediated dendrite formation in primary … di 4dimethylaminophenyl methane msdsWebNew insights into the modular organization and flexibility of the N-terminal half of human cardiac myosin binding protein C (cMyBP-C) and information on the association state … di- 4-tert.-butylcyclohexyl -peroxydicarbonatWebApr 24, 2024 · C-terminal binding protein 2 (CtBP2) is elevated in epithelial ovarian cancer, especially in the aggressive and highly lethal subtype, high-grade serous ovarian cancer (HGSOC). However, whether ... di 3 5 5-trimethylhexanoyl peroxidecinci red stockings